𝔖 Bobbio Scriptorium
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Azido derivative of tricar☐ylic acid for photoaffinity labeling

✍ Scribed by Szewczyk, Adam; Claeys, Dirk; Mertens, Wim; Azzi, Angelo

Book ID
123007376
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
241 KB
Volume
1073
Category
Article
ISSN
0304-4165

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The unstable metabolic inte~ediate 'A-py~oiine-5-ca~oxylic acid (P5C or glutamic semiaidehyde) cannot be isolated as achemically pure solid because of its irreversible and concentration-dependent reaction with itself. This has been avoided by preparing it in dilute solution by periodate oxidation of