✦ LIBER ✦

Azetidine-2-carboxylic Acid. From Lily of the Valley to Key Pharmaceuticals

✍ Scribed by Francois Couty; Gwilherm Evano

Publisher: John Wiley and Sons
Year: 2006
Weight: 8 KB
Volume: 37
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.200652239

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Mutant cell lines resistant to azetidine

Mutant cell lines resistant to azetidine-2-carboxylic acid: Alterations in the synthesis of proline from glutamic acid

✍ Ronna F. Lodato; Robert J. Smith; David L. Valle; Kathleen Crane 📂 Article 📅 1984 🏛 John Wiley and Sons 🌐 English ⚖ 674 KB

Two mutant Chinese hamster lung fibroblast lines have been isolated that are resistant to the the toxic proline analog L-azetidine-2-carboxylic acid. The line designated AZCA-1 has 30-fold elevated activity of pyrroline-5-carboxylate synthase and a large increase in the rate of proline production an

Stereochemical effects in the reactions

Stereochemical effects in the reactions of n-alkyl-4-substituted azetidine 2-carboxylic acids with oxalyl chloride. Rearrangement to chloro-γ-lactams.

✍ Harry H. Wasserman; William T. Han; John M. Schaus; John W. Faller 📂 Article 📅 1984 🏛 Elsevier Science 🌐 French ⚖ 216 KB

On the mechanism of the hydrogen transfe

On the mechanism of the hydrogen transfer from H2OCO to γ-keto-α-hydroxy carboxylic acids to yield γ-keto acids catalyzed by a PdCl2(PPh3)2 precursor in combination with hydrochloric acid

✍ G. Cavinato; L. Toniolo 📂 Article 📅 1996 🏛 Elsevier Science 🌐 English ⚖ 631 KB

The catalytic system PdCI,(PPh,),-HCI is highly active and selective in the hydrogen transfer reaction from H,O-CO to PhCOCH,CHOHCOOH which yields the corresponding y-keto acid PhCOCH,CH,COOH, with concomitant evolution of C02. An increase of temperature, pressure of carbon monoxide and catalyst con