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Azelnidipine inhibits aldosterone synthesis and secretion in human adrenocortical cell line NCI-H295R

✍ Scribed by Tsuyoshi Isaka; Keiichi Ikeda; Yuko Takada; Yuri Inada; Katsuyoshi Tojo; Naoko Tajima

Book ID
113588049
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
315 KB
Volume
605
Category
Article
ISSN
0014-2999

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Inhibitory effects of digoxin and ouabai
Inhibitory effects of digoxin and ouabain on aldosterone synthesis in human adrenocortical NCI-H295 cells
✍ Mei-Mei Kau; Shu-Fen Kan; Jiing-Rong Wang; Paulus S. Wang πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 English βš– 325 KB

## Abstract The present study was to investigate the effects and action mechanisms of digoxin and ouabain on steroidogenesis in human adrenocortical NCI‐H295 cells. Administration of digoxin or ouabain for 24 h decreased the basal and angiotensin II (Ang II)‐stimulated release of aldosterone by NCI