Azaprostanoids I. Synthesis of (RAC)-8-aza-11-deoxy-15-deoxy-16-hydroxy-16-methylprostaglandins

✍ Scribed by Chia-Lin J Wang

• Publisher: Elsevier Science
• Year: 1982
• Tongue: French
• Weight: 208 KB
• Volume: 23
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(00)87023-9

✦ Synopsis

A total synthesis of the title compounds by employing a stereoselective Wittig reaction is described. n In recent years a considerable number of azaprostaglandfnL and aza-prostacyclin3 analogs have been synthesized. One of the most interesting is