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Azabenzocycloheptenones. Part XVIII. Amines and amino-ketones of the tetrahydro-3-benzazepin-1-one series

✍ Scribed by Lennon, Mary; McLean, Angus; Proctor, George R.; Sinclair, Ian W.


Book ID
111919475
Publisher
Royal Society of Chemistry
Year
1975
Weight
576 KB
Volume
7
Category
Article
ISSN
1472-7781

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## Abstract A series of 4‐amino‐tetrahydro‐2‐benzazepin‐3‐one derivatives (Ac–Aba–Xxx–NHMe) were prepared as tetrapeptide mimetics. Considering the structural resemblance with the so‐called Freidinger lactams, their propensity to adopt a β‐turn conformation was investigated by NMR spectroscopy (sol