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Axoplasmic transport: Differential inhibition by cytochalasin-B

✍ Scribed by Fernandez, Hugo L. ;Samson, Frederick E.

Publisher: John Wiley and Sons
Year: 1973
Tongue: English
Weight: 320 KB
Volume: 4
Category: Article
ISSN: 0022-3034
DOI: 10.1002/neu.480040305

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✦ Synopsis

Abstract

Slow (1 mm/day) and fast (10mm/day) axoplasmic transport of labelled protein, shown by the movement of sharp peaks of radioactivity along the crayfish nerve cord, are blocked by cytochalasin‐B. Labelled proteins in the slow peak maintain their sharp distribution; however, those in the fast peak disperse over a broad area after the drug‐induced blockage.

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