## Abstract Axonal transport of cytoskeletal proteins has not yet been extensively studied in the brain proper, in contrast to the peripheral nerves and optic nerves. The authors have developed a means for the study of transport of cytoskeletal proteins in axons of hippocampal pyramidal cells. Prot
Axonal transport of cytoskeletal proteins in aluminum toxicity
โ Scribed by Kenneth S. Kosik; Alan H. McCluskey; Francis X. Walsh; Dennis J. Selkoe
- Publisher
- Springer-Verlag
- Year
- 1983
- Tongue
- English
- Weight
- 835 KB
- Volume
- 3
- Category
- Article
- ISSN
- 1044-7393
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract The relative abundance of several axonal cytoskeletal proteins was determined by immunoassay at various sites in the peripheral and central nervous systems of adult rats. Within the peripheral nervous system, the ratio of tubulin to neurofilaments was greatest for nerves composed of unm
In the present investigation, we have studied the effects of aluminum (10 mg/kg of body weight per day, i.p.) and desferrioxamine (6 mg/kg of body weight per day, i.p.) alone and in combination for 4 weeks on the regulation of phosphorylation of neuronal proteins. A marked decrease in the biological