Axonal Polypeptides Cross-Reactive with Antibodies to Neurofilament Proteins
β Scribed by Beverly A. Brown; Ronald E. Majocha; Donna M. Staton; Charles A. Marotta
- Book ID
- 111172513
- Publisher
- John Wiley and Sons
- Year
- 1983
- Tongue
- English
- Weight
- 991 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0022-3042
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract We report a 74βyearβold woman with a slowly progressive sensory motor axonal neuropathy and a monoclonal IgGβ~ΞΊ~ that bound to a 68βkd axonal protein identified as the low molecular weight neurofilament protein. The sera of control subjects and disease controls did not bind to neurofila
An antibody prepared against purified 200-kDa neurofilament (NF) subunit was found to cross-react with a high molecular weight polypeptide present in rat brain cytoskeletal extracts starting from early postnatal development. This polypeptide was found to be highly concentrated in microtubule prepara