preparation with clear graphs, tables, charts, and pictures documenting all steps of purification or preparation. The growth factors and substrate-modifying materials described are wide-ranging in their effects and useful in many culture systems. The editors have achieved their goal in constructing
Axon or dendrite? cell biology and molecular pathways for neuronal cell asymmetry
โ Scribed by Masashi Kishi
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 98 KB
- Volume
- 86
- Category
- Article
- ISSN
- 0360-4012
No coin nor oath required. For personal study only.
โฆ Synopsis
Abstract
Young neurons polarize by specializing axons and dendrites from immature neurites. After synapse formations, they transmit electrical activity along the axonโdendrite axis, thereby working as functional units of the neural circuits. This axonโdendrite asymmetry is referred to as neuronal polarity. Although a great number of cell biological studies in vitro had been performed, little was known about the molecular events that establish the polarity. In the last several years, rapid advancement in molecular and genetic studies has unraveled the multiple signaling pathways. This paper summarizes current perspectives on the cell and molecular biological mechanisms of the neuronal polarization, to clarify future directions in this growing research field. ยฉ 2007 WileyโLiss, Inc.
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