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Axon Guidance: Mice and Men Need Rig and Robo

✍ Scribed by Sarah Guthrie

Book ID
113558992
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
84 KB
Volume
14
Category
Article
ISSN
0960-9822

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Mice lacking p35, an activator of cdk5 in the central nervous system (CNS), exhibit defects in a variety of CNS structures, most prominently characterized by a disruption in the laminar structure of the neocortex (Chae et al., 1997). In addition, alterations of certain axonal fiber tracts are found