Axial BMD, change in BMD and bone turnover do not predict breast cancer incidence in early postmenopausal women

The vitamin D analogue 2MD increases bon

The vitamin D analogue 2MD increases bone turnover but not BMD in postmenopausal women with osteopenia: Results of a 1-year phase 2 double-blind, placebo-controlled, randomized clinical trial

✍ Hector F DeLuca; Wendy Bedale; Neil Binkley; J Chris Gallagher; Michael Bolognes 📂 Article 📅 2011 🏛 American Society for Bone and Mineral Research 🌐 English ⚖ 215 KB 👁 1 views

## Abstract Most osteoporosis drugs act by inhibiting bone resorption. A need exists for osteoporosis therapies that stimulate new bone formation. 2‐Methylene‐19‐nor‐(20__S__)‐1α,25‐dihydroxyvitamin D~3~ (2MD) is a vitamin D analogue that potently stimulates bone formation activity in vitro and in