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Awakening gene therapy with Sleeping Beauty transposons

✍ Scribed by Jeffrey J Essner; R Scott McIvor; Perry B Hackett

Book ID
116383371
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
152 KB
Volume
5
Category
Article
ISSN
1471-4892

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## Abstract A major problem in gene therapy is the determination of the rates at which gene transfer has occurred. Our work has focused on applications of the __Sleeping Beauty__ (SB) transposon system as a non‐viral vector for gene therapy. Excision of a transposon from a donor molecule and its in