Avidity of IgG antibodies distinguishes primary from non-primary cytomegalovirus infection in pregnant women
✍ Scribed by Bodéus, Monique; Feyder, Sandra; Goubau, Patrick
- Book ID
- 122513165
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- English
- Weight
- 105 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0928-0197
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A newly developed IgG antibody avidity test for human herpesvirus-6 (HHV-6) was used in a study of primary and recurrent HHV-6 antibody responses in immunocompromised solid organ graft recipients. In a primary HHV-6 infection low avidity antibody was detected which matured to high avidity within 5 m
Cytomegalovirus (CMV) is probably the most common agent of prenatal infection of the newborn, and one of 20 congenitally infected newborns shows serious symptoms. It was therefore considered important to be able to differentiate primary CMV from reactivation in pregnant females. A urea denaturation