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Avian sarcoma virus-transforming protein, pp60src shows protein kinase activity specific for tyrosine

✍ Scribed by Collett, Marc S.; Purchio, A. F.; Erikson, R. L.


Book ID
109718576
Publisher
Nature Publishing Group
Year
1980
Tongue
English
Weight
476 KB
Volume
285
Category
Article
ISSN
0028-0836

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Conformational searches on three closely related pp60 c-src protein tyrosine kinase inhibitors of varying potencies were performed to determine a structural basis for their activity. The first was a linear peptide (PDNEYAFFQf), the second its 10-membered cyclic analogue, and the third a cyclic analo