๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Avian B cell development: lessons from transgenic models

โœ Scribed by Camil E Sayegh; Mira A Rao; Michael J.H Ratcliffe


Book ID
117336982
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
138 KB
Volume
72
Category
Article
ISSN
0165-2427

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To study the molecular mechanism for the development of B-cell dominant autoimmune diseases, several autoantibody transgenic mouse models were established. These studies have revealed that the escape of autoreactive B cells from clonal deletion or functional inactivation (clonal anergy) alone is not