✦ LIBER ✦

Avermectin-milbemycin studies. 4. An expedient two-step preparation of p-hydroxybenzoates

✍ Scribed by Amos B. Smith III; S.Nicholas Kileńyi

Publisher: Elsevier Science
Year: 1985
Tongue: French
Weight: 256 KB
Volume: 26
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)88919-4

No coin nor oath required. For personal study only.

✦ Synopsis

Dianions derived from a variety of 1,3-diketones react with Z-ethyl-3-bromopropenoate to afford unsaturated diketoesters which upon treatment with base undergo facile cyclization-dehydration to p-hydroxybenzoates.