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Autoxidation of the serotonergic neurotoxin 5,7-dihydroxytryptamine

โœ Scribed by Tabatabaie, Tahereh; Wrona, Monika Z.; Dryhurst, Glenn

Book ID
126957045
Publisher
American Chemical Society
Year
1990
Tongue
English
Weight
803 KB
Volume
33
Category
Article
ISSN
0022-2623

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Peroxidase-promoted oxidation and peroxidation of the serotonergic neurotoxin 5,7-dihydroxytryptamine
โœ Diana Metodiewa; H. Brian ๐Ÿ“‚ Article ๐Ÿ“… 1992 ๐Ÿ› Springer ๐ŸŒ English โš– 780 KB

Spectral data provide the first evidence that lactoperoxidase, a model enzyme for most mammalian peroxidases, catalyzed the one-electron oxidation and/or peroxidation of 5,7-dihydroxytryptamine. This process correlates with the production of superoxide radicals as is evident from the observed inhibi