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Autosomal phosphoglycerate kinase linked to mouse major histocompatibility complex

✍ Scribed by Eicher, Eva M. ;Cherry, Marianna ;Flaherty, Lorraine

Book ID
104692828
Publisher
Springer
Year
1978
Tongue
English
Weight
342 KB
Volume
158
Category
Article
ISSN
0026-8925

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✦ Synopsis

The mouse autosomal locus that determines the form of phosphoglycerate kinase found only in testes is shown here to be closely linked to but not included within the major histocompatibility complex on chromosome 17. Data are presented that strongly favor the location of this locus, designated Pgk-2, distal to H-2, Qa-1, and Qa-2, and closely associated with T1a. The Pgk-2 strain distribution pattern for 103 inbred and congenic strains of mice is given. Because Pgk-2 is polymorphic among inbred strains, it should be of value in linkage studies.

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✍ Jack R. Battisto; R. N. Smith; Karla Beckman; Mona Sternlicht; Wanda L. Welles πŸ“‚ Article πŸ“… 1982 πŸ› John Wiley and Sons 🌐 English βš– 615 KB

## Abstract The heritability of adjuvant‐induced arthritis in rats of the DA and Fisher 344 strains was examined. Development of arthritic lesions in response to a single injection of supplemented Freund's complete adjuvant has been found to be controlled by an autosomal, dominant gene locus, Ar. T