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Autosomal dominant retinitis pigmentosa: Linkage to rhodopsin and evidence for genetic heterogeneity

✍ Scribed by Jane Farrar, G.; McWilliam, Peter; Bradley, Daniel G.; Kenna, Paul; Lawler, Mark; Sharp, Elizabeth M.; Humphries, Marian M.; Eiberg, Hans; Micheal Conneally, P.; Trofatter, James A.


Book ID
122778738
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
716 KB
Volume
8
Category
Article
ISSN
0888-7543

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No evidence of linkage between the locus
✍ Jacqueline B. JimΓ©nez; Christine Samanns; Anke Watty; Johann Pongratz; Jane E. O πŸ“‚ Article πŸ“… 1991 πŸ› Springer 🌐 English βš– 224 KB

A linkage analysis has been performed on three Australian families segregating for autosomal dominant retinitis pigmentosa (ADRP). No evidence of linkage has been found in any of the pedigrees studied between the locus D3S47 and the gene for ADRP. The D3S47 locus was found to show very close linkage