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Autosomal dominant centronuclear myopathy: Report of a new family with clinical features simulating facioscapulohumeral syndrome

✍ Scribed by Kevin J. Felice; Margaret L. Grunnet


Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
304 KB
Volume
20
Category
Article
ISSN
0148-639X

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✦ Synopsis


The centronuclear myopathies are a clinically and genetically heterogeneous group of disorders which share similar histological features on muscle biopsy. The familial cases have been classified genetically as X-linked or autosomal in inheritance. The autosomal forms usually have a later onset and milder course as compared to the X-linked form. Thirteen families with autosomal dominant centronuclear myopathy have been previously described. We describe an additional family with unique clinical features which initially suggested a facioscapulohumeral syndrome.