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Autoregulation enables different pathways to control CCAAT/enhancer binding protein β (C/EBPβ) transcription

✍ Scribed by Monika Niehof; Stefan Kubicka; Lars Zender; Michael P. Manns; Christian Trautwein

Book ID: 115631074
Publisher: Elsevier Science
Year: 2001
Tongue: English
Weight: 683 KB
Volume: 309
Category: Article
ISSN: 0022-2836
DOI: 10.1006/jmbi.2001.4708

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## Abstract CCAAT/enhancer binding protein δ (C/EBPδ) plays a key role in mammary epithelial cell G~0~ growth arrest. C/EBPδ gene expression is down‐regulated in rodent mammary tumorigenesis and in human breast cancer, suggesting that “loss of function” alterations in C/EBPδ gene expression are com