Autoreactivity and CD5+ B cells
β Scribed by K. Hayakawa
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- English
- Weight
- 935 KB
- Volume
- 2
- Category
- Article
- ISSN
- 0952-7915
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Suppressive activities involving T-B and T-T cell interactions are important to maintain immune system homeostasis. Negative control of IgG2a b+ B cells by anti-IgG2a b T cells derived from Igha mice has been well documented. Nevertheless the real contribution of anti-IgG2a b T cells, endogenously m
In this study the mode of expression of CD5 by human tonsillar CD5-B cells after stimulation with different agents was investigated. Resting B cells were separated into CD5+ and CD5cells and the two cell fractions exposed to phorbol 12-myristate 13-acetate (PMA). CD5-B cells expressed CD5 and maximu