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Autophagy Gene Polymorphisms Influence the Interaction of E.Coli and Macrophages in Crohn's Disease

✍ Scribed by Tim Elliott; Natalie J. Prescott; Barry N. Hudspith; Neil B. Rayment; John Hermon-Taylor; Jonathan Brostoff; Christopher G. Mathew; Jeremy D. Sanderson

Book ID
119431955
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
177 KB
Volume
140
Category
Article
ISSN
0016-5085

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## Background: The autophagy pathway has been linked with Crohn's disease (CD) through association of the ATG16L1 and IRGM genes with susceptibility for CD, and also to the Nod2 pathway, involved in CD. Our aim was to investigate polymorphisms in selected autophagy genes for their association with