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Autophagy at the gut interface: Mucosal responses to stress and the consequences for inflammatory bowel diseases

โœ Scribed by Alan Huett; Ramnik J. Xavier


Book ID
102861125
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
606 KB
Volume
16
Category
Article
ISSN
1078-0998

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โœฆ Synopsis


Autophagy is a conserved homeostatic process by which cells degrade and recycle cytoplasmic contents and organelles. Recently, autophagy has come to prominence as a factor in many disease states, including inflammatory bowel diseases. In this review we explore the recent discoveries in autophagy and how these relate to the special conditions experienced by the gut mucosa. We will pay particular attention to autophagy as an innate immune process and its role in the development and education of the adaptive immune system.


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