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Autophagy and neurodegeneration

โœ Scribed by Annamaria Ventruti; Ana Maria Cuervo


Book ID
107543583
Publisher
Springer
Year
2007
Tongue
English
Weight
181 KB
Volume
7
Category
Article
ISSN
1528-4042

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Chaperone-mediated autophagy (CMA) contributes to selective degradation of individual soluble proteins in lysosomes. Unique to this type of autophagy is the fact that proteins reach the lysosomal lumen for degradation by directly crossing the lysosomal membrane, in contrast with the vesicle-mediated