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Autophagy 16-like 1 rs2241880 G allele is associated with Crohn’s disease in German children

✍ Scribed by Martin Lacher; Sebastian Schroepf; Antje Ballauff; Peter Lohse; Dietrich Von Schweinitz; Roland Kappler; Sibylle Koletzko


Book ID
114816170
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
191 KB
Volume
98
Category
Article
ISSN
0803-5253

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Autophagy gene ATG16L1 but not IRGM is a
✍ Devendra K. Amre; David R. Mack; Kenneth Morgan; Alfreda Krupoves; Irina Costea; 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 94 KB 👁 2 views

Background: Recent genome-wide studies have implicated the autophagy genes ATG16L1 and IRGM in the pathogenesis of Crohn's disease (CD). We investigated whether these genes were associated with CD in Canadian children. ## Methods: A case-control study was carried out at 2 pediatric gastroenterolog