HAMLET (human Ξ±-lactalbumin made lethal
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Sonja Aits; Lotta Gustafsson; Oskar Hallgren; Patrick Brest; Mattias Gustafsson;
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Article
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2009
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John Wiley and Sons
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French
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## Abstract HAMLET, a complex of partially unfolded Ξ±βlactalbumin and oleic acid, kills a wide range of tumor cells. Here we propose that HAMLET causes macroautophagy in tumor cells and that this contributes to their death. Cell death was accompanied by mitochondrial damage and a reduction in the l