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Autonomic symptoms in patients and pre-manifest mutation carriers of Huntington’s disease

✍ Scribed by N. A. Aziz; G. V. Anguelova; J. Marinus; J. G. Van Dijk; R. A. C. Roos

Book ID
111066296
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
91 KB
Volume
17
Category
Article
ISSN
1351-5101

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## Abstract Huntington's disease (HD) is an autosomal dominantly inherited neurodegenerative disorder caused by a CAG repeat expansion in the __IT‐15__ gene; however, it remains unknown how the mutation leads to selective neurodegeneration. Several lines of evidence suggest impaired mitochondrial f