Autonomic dysfunction in presymptomatic and early symptomatic Huntington’s disease
✍ Scribed by J. Kobal; Z. Melik; K. Cankar; F. F. Bajrovic; B. Meglic; B. Peterlin; M. Zaletel
- Book ID
- 109339018
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 173 KB
- Volume
- 121
- Category
- Article
- ISSN
- 0001-6314
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📜 SIMILAR VOLUMES
## Abstract The purpose of this study was to quantify gait impairments in presymptomatic and symptomatic Huntington's disease (HD) subjects, and examine sensitivity of gait measures. Our sample (n = 65) included presymptomatic mutation carriers (PMC) (n = 15), symptomatic HD subjects (SHD) (n = 30)
Previous research by our group demonstrated a longitudinal change in caudate volume for symptomatic subjects with Huntington's disease (HD), and suggested that volume of the caudate may be a useful outcome measure for therapeutic studies in symptomatic patients. The current study was designed to det