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Autonomic and peripheral neuropathy in endstage liver disease and following liver transplantation

โœ Scribed by Alan J. McDougall; Leo Davies; Geoff W. McCaughan


Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
78 KB
Volume
28
Category
Article
ISSN
0148-639X

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โœฆ Synopsis


Abstract

Severe chronic liver disease may be associated with a peripheral somatic and an autonomic neuropathy. There are only a limited number of reports on the incidence and features of these neuropathies. In addition the effects of liver transplantation on these neuropathies have not been well studied. We examined peripheral somatic and autonomic nerve function in 42 patients with endstage liver disease prior to transplantation and also examined the effect of liver transplantation on these neuropathies in 14 patients. Peripheral somatic neuropathy (93%) and autonomic neuropathy (50%) were common in patients with endstage liver disease and were more frequent than previously reported. Abnormalities improved in some patients after liver transplantation, particularly if there was return of normal hepatic function. Muscle Nerve 28: 595โ€“600, 2003


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