## Abstract Ligand–protein docking is increasingly used in Drug Discovery. The initial limitations imposed by a reduced availability of target protein structures have been overcome by the use of theoretical models, especially those derived by homology modeling techniques. While this greatly extende
✦ LIBER ✦
Automatic prediction of flexible regions improves the accuracy of protein-protein docking models
✍ Scribed by Xiaohu Luo; Qiang Lü; Hongjie Wu; Lingyun Yang; Xu Huang; Peide Qian; Gang Fu
- Book ID
- 113053327
- Publisher
- Springer-Verlag
- Year
- 2011
- Tongue
- English
- Weight
- 470 KB
- Volume
- 18
- Category
- Article
- ISSN
- 1610-2940
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## Abstract Modern structure‐based drug design aims at accounting for the intrinsic flexibility of therapeutic relevant targets. Over the last few years a considerable amount of docking approaches that encounter this challenging problem has emerged. Here we provide the readership with an overview o