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Automatic on-line growth estimation method for outdoor algal biomass production

✍ Scribed by H. Guterman; S. Ben-Yaakov; A. Vonshak


Publisher
John Wiley and Sons
Year
1989
Tongue
English
Weight
834 KB
Volume
34
Category
Article
ISSN
0006-3592

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✦ Synopsis


An on-line measuring procedure for estimating productivity in outdoor algal cultures was developed and tested experimentally. The procedure is based on a previously described method for on-line measuring net O(2) production rate (OPR). The data obtained by this method was found to correlate well with the conventional procedures for estimation productivity by measuring the changes in biomass concentration in the culture. The new procedure seems to be superior to the latter since it can be carried out in an almost continuous way and can give immediate indication on the productivity. OPR could be used to monitor on-line the photosynthetic and/or respiration activity in small research fermentors or in large-scale open systems outdoors.


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## Abstract This article describes a novel bioreactor configuration for production optimization of recombinant proteins in __Escherichia coli__. Inducer addition and harvesting are controlled on‐line based on indirect estimation of biomass concentration and specific growth rate from addition of NaO