✦ LIBER ✦

Automated strategies for obtaining standardized collisionally induced dissociation spectra on a benchtop ion trap mass spectrometer

✍ Scribed by Linda L. Lopez; Philip R. Tiller; Michael W. Senko; Jae C. Schwartz

Book ID: 101237781
Publisher: John Wiley and Sons
Year: 1999
Tongue: English
Weight: 182 KB
Volume: 13
Category: Article
ISSN: 0951-4198
DOI: 10.1002/(sici)1097-0231(19990430)13:8<663::aid-rcm538>3.0.co;2-h

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✦ Synopsis

An automated method for obtaining standardized collisionally induced dissociation (CID) spectra using two novel ion activation techniques on a quadrupole ion trap mass spectrometer is described. This strategy simultaneously produces optimal CID spectra "on-the-fly" and maximizes the amount of structurally specific fragment ions obtained in a single experiment, thus eliminating the need for individual tuning of specific mass-to-charge ratios and permitting fragmentation conditions to be more consistently reproduced.