## Communicated by A. Jaime Cutticchia Information theory-based software tools have been useful in interpreting noncoding sequence variation within functional sequence elements such as splice sites. Individual information analysis detects activated cryptic splice sites and associated splicing regu
Automated splicing mutation analysis by information theory
β Scribed by Vijay K. Nalla; Peter K. Rogan
- Book ID
- 102262909
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 50 KB
- Volume
- 29
- Category
- Article
- ISSN
- 1059-7794
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Splice site nucleotide substitutions can be analyzed by comparing the individual information contents (R i , bits) of the normal and variant splice junction sequences . In the present study, we related splicing abnormalities to changes in R i values of 111 previously reported splice site substitutio
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