Automated rheumatoid factor assay in a population of patients with rheumatic disease
β Scribed by Eric P. Gall; David W. Templin; William R. Dito
- Publisher
- John Wiley and Sons
- Year
- 1978
- Tongue
- English
- Weight
- 373 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0004-3591
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The frequency of a recently described point mutation of the ciliary neurotrophic factor (CNTF) gene was investigated in a population of 154 German patients with motor neuron disease (MND). Twenty-two percent of the patients were heterozygous, 2% homozygous for the CNTF mutation. Since the gene defec
## Abstract ## Objective Recent studies of 2 complex diseases, rheumatoid arthritis (RA) and Crohn's disease (CD), showed associations with genes mapping to the cytokine gene cluster on 5q31. In particular, a functional singleβnucleotide polymorphism (SNP) mapping to intron 1 of the organic cation