Automated production and quality control of 15O2 and C15O2
β Scribed by K. Strijckmans; J. Sambre; F. De Guchteneire
- Publisher
- John Wiley and Sons
- Year
- 1989
- Tongue
- French
- Weight
- 107 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0022-2135
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π SIMILAR VOLUMES
## Abstract A general synthetic approach for the synthesis of ^15^Nβ and ^17^Oβdoubly labelled pyrimidine nucleosides is described. The ^15^N isotopes in uridine and the ^17^O isotope in the ureaβderived carbonyl group of uridine and cytidine originate from (^15^N~2~)[^17^O]urea (5) which was synth
## Abstract The 5βmethyl(^15^N~2~)[__O__^2^,__O__^4^β^17^O~2~]uridine (= (^15^N~2~)[__O__^2^,__O__^4^β^17^O ~2~]ribosylthymine; 15) was synthesized and analyzed by ^15^Nβ and ^17^OβNMR spectroscopy. (^15^N~2~)Urea was condensed with 2,3βdibromoβ2βmethylpropanoyl chloride (3) and cyclized to form (^
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