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Automated nephelometric immunoassays with novel shell/core particles

✍ Scribed by Wolfgang H. Kapmeyer; Hans-Erwin Pauly; Peter Tuengler

Publisher
John Wiley and Sons
Year
1988
Tongue
English
Weight
593 KB
Volume
2
Category
Article
ISSN
0887-8013

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✦ Synopsis

Nephelometry has become a very reliable cores are prepared by emulsion polymeriand convenient method for immunoas-zation, giving particles with a well-defined says. Recent innovations in polymer chem-size. The particle size has been optimized istry have led to the design of highly to fulfill the requirements for nephelometsensitive and reproducible immunoassays ric analysis. The shells consist of a polystyfor the Behring Nephelometer Analyzer. renelpolymethacrylatelpolymethacrylami- The principle of particle-enhanced immu-doacet-aldehyde dipentylacetal copolymer, noassays has led to the development of which allows a covalent binding of the imnew polymer particles. Key advances inmunochemicals of interest. Using these clude the preparation and use of particles particles, a method for the determination with polystyrene cores covered by thin of C-reactive protein has been worked out. shells with chemically reactive groups. The

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