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Automated micro method for enzymatic l(+) and d(−) lactic acid determinations in biological fluids containing cellular extracts

✍ Scribed by S.Richard Goodall; Floyd M. Byers


Publisher
Elsevier Science
Year
1978
Tongue
English
Weight
410 KB
Volume
89
Category
Article
ISSN
0003-2697

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✦ Synopsis


Automated micro methods for the rapid assay of L(+) and D(-) lactic acid in rumen fluid and other biological extracts were developed using an Auto-samplerpump system and UV-Vis Spectrophotometer. Both involved the use of L(+) and D(-)

LDH enzymes, with the reduction of NAD+ to NADHz measured at 340 nm. These enzymatic methods are highly specific for either isomer, run at a rate of 60 samples/hr, use minimal quantities of reagents, and require only 40 to 80 ~1 of sample. ' Approved for publication as Journal Article No. 161-77 of the Ohio Agricultural Research and Development Center,