Determination of a ‘GW cocktail’ of cyto
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Rebecca J. Scott; Jonathan Palmer; Ivor A. S. Lewis; Stephen Pleasance
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Article
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1999
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John Wiley and Sons
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English
⚖ 196 KB
👁 2 views
A mass spectrometry based method for the simultaneous determination of an in vivo Greenford-Ware or 'GW cocktail' of CYP450 probe substrates and their metabolites in both human plasma and urine is described. The probe substrates, caffeine, diclofenac, mephenytoin, debrisoquine, chlorzoxazone and mid