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Automated determination of total captopril in urine by liquid chromatography with post-column derivatization coupled to on-line solid phase extraction in a sequential injection manifold

✍ Scribed by Theano D. Karakosta; Paraskevas D. Tzanavaras; Demetrius G. Themelis


Book ID
116905587
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
289 KB
Volume
88
Category
Article
ISSN
0039-9140

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A high-performance liquid chromatographic system, combining solid-phase extraction and automated precolumn derivatization is described for the routine determination of methotrexate in human plasma. The sample extraction and elution onto the analytical column were performed automatically and concomit