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Automated design of specificity in molecular recognition

โœ Scribed by Havranek, James J.; Harbury, Pehr B.

Book ID
109965415
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
938 KB
Volume
10
Category
Article
ISSN
1072-8368

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The Random Energy Model of statistical physics is applied to the problem of the specificity of recognition between two biological (macro)molecules forming a non-covalent complex. In this model, the native mode of association is separated by an energy gap from a large body of non-native modes. Wherea