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Automated assay for non-transferrin-bound iron in serum samples

โœ Scribed by Prezelj, Marija; Knap, Bojan


Book ID
120224339
Publisher
Walter de Gruyter GmbH & Co. KG
Year
2010
Tongue
English
Weight
132 KB
Volume
48
Category
Article
ISSN
1434-6621

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โœ William Breuer; Z.Ioav Cabantchik ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 114 KB

We introduce a method for monitoring non-transferrin-bound iron (NTBI), a labile and potentially toxic form of serum iron associated with imbalanced iron metabolism. The assay employs fluorescein-labeled apotransferrin (Fl-aTf), which undergoes fluorescence quenching upon binding iron. It has the ad