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Autologous tumor-derived heat-shock protein peptide complex-96 (HSPPC-96) in patients with metastatic melanoma

โœ Scribed by Omar Eton; Merrick I Ross; Mary Jo East; Paul F Mansfield; Nicholas Papadopoulos; Julie A Ellerhorst; Agop Y Bedikian; Jeffrey E Lee


Book ID
119905642
Publisher
BioMed Central
Year
2010
Tongue
English
Weight
395 KB
Volume
8
Category
Article
ISSN
1479-5876

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Heat shock protein (HSP)-peptide complexes isolated from murine cancers elicit protective immunity and T lymphocytes specific for the cancer from which the HSPs are isolated. A pilot study was designed to test the feasibility, immunogenicity and toxicity of such treatment in cancer patients. Sixteen