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Autologous stem cell transplantation in multiple myeloma after VAD and EDAP courses: a high incidence of oligoclonal serum Igs post transplantation

✍ Scribed by Sibinga, C Th Smit; Bos, N A; Vellenga, E; Hovenga, S; de Wolf, J ThM; Guikema, J E J; Klip, H; Smit, J W


Book ID
110012427
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
67 KB
Volume
25
Category
Article
ISSN
0007-1188

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## Abstract Dickkopf‐1 (DKK‐1) protein, a soluble inhibitor of Wnt signalling, has been implicated in the pathogenesis of myeloma bone disease through the suppression of osteoblast differentiation. In this study, serum concentrations of DKK‐1 were measured in 50 myeloma patients (32 at diagnosis an