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Autologous glioma cell vaccine admixed with interleukin-4 gene transfected fibroblasts in the treatment of patients with malignant gliomas

✍ Scribed by Hideho Okada; Frank S Lieberman; Kevin A Walter; L Dade Lunsford; Douglas S Kondziolka; Ghassan K Bejjani; Ronald L Hamilton; Alejandro Torres-Trejo; Pawel Kalinski; Quan Cai; Jennifer L Mabold; Howard D Edington; Lisa H Butterfield; Theresa L Whiteside; Douglas M Potter; S Clifford Schold; Ian F Pollack

Book ID
119905477
Publisher
BioMed Central
Year
2007
Tongue
English
Weight
551 KB
Volume
5
Category
Article
ISSN
1479-5876

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## Abstract Interferon‐β (IFN‐β) has been used as an antitumor drug against human glioma, melanoma and medulloblastoma since the 1980s. Recently, we developed a new gene therapy using the __IFN__‐β gene against malignant gliomas and then began clinical trials in 2000. Since stimulation of immune sy