Paradigm shifts in Alzheimer's disease a
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Marina D. Kirkitadze; Gal Bitan; David B. Teplow
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Article
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2002
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John Wiley and Sons
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English
β 112 KB
Alzheimer's disease (AD) is a progressive, neurodegenerative disorder characterized by amyloid deposition in the cerebral neuropil and vasculature. These amyloid deposits comprise predominantly fragments and full-length (40 or 42 residue) forms of the amyloid beta-protein (Abeta) organized into fibr