✦ LIBER ✦

Autoimmunity in diabetic autonomic neuropathy: does the immune system get on your nerves?

✍ Scribed by Ejskjaer, N.T.; Zanone, M.M.; Peakman, M.

Publisher: John Wiley and Sons
Year: 1998
Tongue: English
Weight: 160 KB
Volume: 15
Category: Article
ISSN: 0742-3071
DOI: 10.1002/(sici)1096-9136(199809)15:9<723::aid-dia674>3.0.co;2-7

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✦ Synopsis

Symptomatic autonomic neuropathy is a devastating occasional complication of diabetes mellitus, especially Type 1. Although the full-blown clinical syndrome is not common, dysfunction of the autonomic nerves is detectable in up to 40 % of Type 1 diabetic patients but its aetiopathogenesis is poorly understood. There is evidence to suggest that the damage to the autonomic nerves may be immune-mediated. This evidence is reviewed in the following article.