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Autoimmunity and tumor immunity induced by immune responses to mutations in self

✍ Scribed by Engelhorn, Manuel E; Guevara-Patiño, José A; Noffz, Gabriele; Hooper, Andrea T; Lou, Olivia; Gold, Jason S; Kappel, Barry J; Houghton, Alan N

Book ID
109932816
Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
325 KB
Volume
12
Category
Article
ISSN
1078-8956

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## Abstract Fluorescein (FITC)‐haptenated mouse spleen cells are capable of inducing a B cell immune response characterized by the production of antibodies directed against hapten‐altered self structures. The induction of this response is thymus‐independent and strictly dependent on the hapten conc