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Autoimmune T cell recognition of human acetylcholine receptor: the sites of T cell recognition in myasthenia gravis on the extracellular part of the α subunit

✍ Scribed by Minako Oshima; Tetsuo Ashizawa; Marilyn S. Pollack; M. Zouhair Atassi


Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
708 KB
Volume
20
Category
Article
ISSN
0014-2980

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The a-subunit of the nicotinic acetylcholine receptor is the major target of the autoimmune response in myasthenia gravis. We investigated the proliferative response of T cells from patients with myasthenia gravis and healthy volunteers to recombinant polypeptides of the human acetylcholine receptor