Autoimmune Polyendocrine Syndromes: Clues to Type 1 Diabetes Pathogenesis
β Scribed by Eystein S. Husebye; Mark S. Anderson
- Book ID
- 108152546
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 202 KB
- Volume
- 32
- Category
- Article
- ISSN
- 1074-7613
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## Abstract Autoimmune polyendocrine syndrome type 1 (APSβ1) is a multiorgan autoimmune disease caused by mutations in the autoimmune regulator (AIRE) gene. Chronic mucocutaneous candidiasis, hypoparathyroidism and adrenal failure are hallmarks of the disease. The critical mechanisms causing chroni
## Abstract Autoimmune polyendocrine syndrome type 1 (APSβ1), also known as Autoimmune Polyendocrinopathy Candidiasis and Ectodermal Dysplasia (APECD) is a disorder caused by mutations in the autoimmune regulator (__AIRE__) gene. In some APSβ1 patients, significant pulmonary disease is observed. Au